Carlos Castrillon, PhD

Instructor

Department of Medicine, Division of Rheumatology · Emory University School of Medicine · Atlanta, GA

B cell illustration

I am a junior faculty scientist at Emory University School of Medicine studying the biology of human B cells and plasma cells, with a focus on autoimmune disease and next-generation therapeutics.

Plasma cell illustration

My research program centers on two main areas: the modulation of BCR signaling in systemic lupus erythematosus (SLE), supported by a career development award from the Lupus Research Alliance, and the use of mRNA technology to modulate and engineer primary human immune cells — both as therapeutics and as tools for basic research and early-stage drug discovery.

mRNA illustration

My work integrates wet- and dry-lab multiomics approaches. I am currently developing my independent program under the mentorship of Dr. Iñaki Sanz and Dr. Frances Eun-Hyung Lee.

google scholar
Carlos Castrillon

Background

Postdoc
With Dr. Michael Carroll at Boston Children's Hospital. Studied B cell responses in lupus using a novel fate-mapping mouse model. Techniques: single-cell RNA-seq, spatial transcriptomics, microscopy, flow cytometry, Luminex assays.
PhD
With Dr. Pierre Bruhns at Institut Pasteur and Dr. Andrew Griffiths at ESPCI, Paris. Developed droplet microfluidics assays for high-throughput antibody discovery and their characterization (BLI, SPR). Also worked with mouse models of immunization and rheumatoid arthritis (K/BxN).
Undergrad
Universidad Peruana Cayetano Heredia, BSc in Biology, Lima, Peru.

Contact

Happy to discuss research, collaborations, or questions about my work. Best reached by email.

carlos.castrillon at emory.edu github / cstrlln linkedin google scholar orcid